I've read the discussions and general policy below, and would like to add comment and see your answers before I change the profiles I manage.
I feel that - in the absence of a profile having a specific title / rank / profession - there can still be some value in using Mr / Ms / Miss / Mrs / Master as prefixes.
Use of "Mr" implies that adult manhood was reached, even if evidence/references or date of marriage / death are not available. "Master" implies the opposite, death before male maturity. "Ms." is of course ambiguous, but having "Mr" or "Ms" stated has value when the first name (e.g. Frances, Georgie, Hester, Jude, Jo, Sammy) could be taken as either sex, and when the parents' names are not listed to show "son of / daughter of". "Mrs" highlights that the married name should normally match that of the husband, and there should also be a maiden name - which is often not the case in the many profiles, especially uploaded trees /ged's. "Miss" implies, for a mature woman, that there is evidence or inference that she never married; or for a younger woman, that her name may change if married.
Hence I feel that there is some value in these titles, if only for verification of other data in the profiles; or inference when such data is absent.
But of course, if it is regarded as Wikitree policy not to generally use these titles as prefixes, then of course I will abide by that without problem.