I don't speak german but here's my best guess....
Vaccination Certificate
Wenzl Benesh child of Wenzl Benesh, 2 1/4 months old, born at 19 Weistlman ? and living in 19 Weistlman? was inoculated by the undersigned in 1849 the 2nd of May with Ruhpedenstoffen and asked (Deci achte ?) Ruhpoden properly survived.
The 10 May 1849 signature
Vaccinator