I only just looked at it because you asked, and I had, what I think is a HUGE change! Even though on my father's side the paper trail all leads to Palermo, Sicily, I am only 30% Southern Italian. The other 20% comes from the Aegean Islands, Greece and Albania, Cyprus, France and the Balkans.
I am also surprised on my maternal side because Wales and England & Northwest Europe are more largely represented. I've lost a lot of Germany, but gained Norway, Scotland, Northern Italy and Easter Europe & Russia. I think my Ireland increased.
Too bad I wasn't able to test my maternal grandparents. My grandmother had deep roots in the US, but my grandfather's parents were both immigrants - one from Germany and one from Ireland.
My daughter still has her indigenous North American though. Interestingly, she inherited both Sweden & Denmark and Spain from me, but I don't show those in my estimate.
Then I looked at my sister's inheritance and her chart looks so different from mine. She has Ireland on our Italian paternal side and Sardinia that I do not. On our maternal side, she has almost equal amounts of England & NW Europe, Ireland and Wales, with a little Scotland thrown in.