Debbie,
I have a huge spreadsheet. It is organized by chromosome and segment. In addition to all of the material from the match I add Wikitree ID if there is one, common ancestors if I have found them. I also add e-mail address and the date I sent an e-mail. If there is a family file at Ancestry I add the link. As I use , Gedmatch, FTDNA and MyHeritage, I show which system produced the match and make a point of identifying those in multiple systems. I make a lot of notes, things like relationships between various kits, for example when I have been able to determine that one kit is for the parent of second kit, I add that note.
I have used spreadsheets for years and am use to using very large ones so this was a logical choice for me. I think of data as a spreadsheet, it is how I visualize data sets. If you are very comfortable with a spreadsheet I think it is a great tool.
In same cases I add color coding for groups. As I have siblings with DNA tests I have subsections for their matches but those are not very large at this time.