I have 3 Samuel Leffels in my tree.
One is Samuel Leffel (1777-1862) and here is the link to his profile. He is married to Dorothy Peery in 1808. This is a close match to your date. And Dorothy died in 1848. So perhaps Samuel remarried and I'm not aware of it. Please take a look at my profile for Samuel http://wikitree.com/wiki/leffel-35.
My understanding is that Samuel also had a son named Samuel. I have no info on him. http://wikitree.com/wiki/leffel-45
Do any of the times or names fit? Would you be so kind as to share the info you have?