I have have an ancestor named John Alexander McLaughlin that lived in Sistersville, Tyler Co. West Virginia 1850's Before migrating into Clay county Illinois. I believe his father, also a John Alexander McLaughlin or Laughlin, lived in Zanesville, Ohio in 1810 or so, then Columbiana Co, OH 1820-1850. 1850 census says he was born in Scotland? I don't know if this particular McLaughlin would fit in with yours or not. But I am not able to get further back than the John Alexander Laughlin or McLaughlin that lived in Zanesville, and Columbiana Co. Ohio.