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Dr Basil Hetzel AC was an Australian medical researcher who made a significant contribution to public health worldwide through his research which identified the link between iodine deficiency and brain development. His work has prevented millions of children from being born with brain damage.[1]
He was born in 1922 and is the eldest of two sons of Kenneth Hetzel, an anaesthetist, and Elinor Watt, both South Australians, Hetzel was born in England while his father was working at the University College Hospital in London. The family, including a younger brother, Peter, returned to South Australia in 1925.[2][3]
Hetzel grew up in Adelaide, South Australia, where he was educated at Kings College and St Peter's College. He graduated in medicine from the University of Adelaide with distinction in 1944. After postgraduate education and research in Adelaide (1945-51); New York (Fulbright Research Scholar (1951-54); and London (1954-55), he returned to the University of Adelaide as Reader and later became the first Michell Professor of Medicine at The Queen Elizabeth Hospital (1956-68).[4]
At that time it had been established that iodine deficiency could lead to goitre and if more severe, to retarded growth and development, particularly brain development, in a condition known as congenital iodine deficiency syndrome, or cretinism. Hetzel's group developed an intervention strategy using iodised oil injections for the correction of severe iodine deficiency and was the first to show that disorders of brain development in the setting of iodine deficiency could be prevented by this approach. Global prevention of this problem became his life’s work, leading to salt iodisation programs in about 130 countries and prevented millions of children from being born with brain damage.[1][5]
Hetzel continued his work in Melbourne, as the first Chair of Social and Preventative Medicine at Monash University, and by 1970 his team demonstrated that correction of iodine deficiency before pregnancy totally prevented endemic cretinism and related conditions. From 1986, as The Commonwealth Scientific and Industrial Research Organisation's (CSIRO) first Chief of the Division of Human Nutrition, he showed that iodine deficiency caused retardation of brain development in sheep and in marmoset monkeys.[4][6]
In 1986, Hetzel initiated and then became Executive Director of the International Council for Control of Iodine Deficiency Disorders (ICCIDD) which is now a global multidisciplinary group of 700 scientists, medical administrators and public health workers from more than 100 countries.[4]
Iodine Deficiency Disorder (IDD) is now recognised by the World Health Organization (WHO) as the most common preventable cause of brain damage in the world with more than 2 billion people at risk in 130 countries.[6] The iodization of salt has reduced the number of iodine deficient countries from 110 in 1993 to only 19 in 2017.[7]
From 1992 to 1998 Hetzel was appointed Chancellor of the newly formed University of South Australia,[1] and Lieutenant Governor of South Australia from 1992-2000.[4] In 2001, The Queen Elizabeth Hospital established The Basil Hetzel Institute for Medical Research in his honour. In 2005 the Health Sciences building at the City East campus of the University of South Australia was named the Basil Hetzel Building.[1]
In 1990 Hetzel was awarded the Companion of the Order of Australia,[8] and the Centenary Medal in 2001.[9] The National Trust named Hetzel as one of Australia’s National Living Treasures in 2004, and in 2015 he was awarded an Honorary Doctorate from the University of Adelaide.[6][10]
Hetzel has an extensive list of over 200 scientific publications and has authored or edited 19 books including “Health and Australian Society” which has sold more than 40,000 copies. He was also author of “The Story of Iodine Deficiency – A Challenge in International Nutrition” which has been translated into French, Spanish, Chinese, Japanese and Russian.[5]
Hetzel married Helen Eyles in St Peters College Chapel on 3rd December 1946.[11] They had five children, three sons and two daughters, before Helen died from cancer in 1980. In 1983 Hetzel married again, to Anne Fisher.[3]
Hetzel died on 4 February 2017. He was honoured with a State Memorial Service at the Bonython Hall, University of Adelaide on 27 February 2017.[4] His remains were cremated at Centennial Park, Pasadena.[12]
For his work on iodine deficiency and its eradication Basil Hetzel has received a number of awards and honours, including:[4]
Fellowships
Awards
See also:
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