Robert Kellogg Crane (December 20, 1919 – October 31, 2010) was an American biochemist best known for his discovery of sodium-glucose cotransport.
Crane was born on December 20, 1919 in Palmyra, New Jersey, to Wilbur Fiske Crane, Jr. architect and engineer, and Mary Elizabeth McHale Crane. He is the grandson of Stephen Crane's brother Wilbur.
Crane's discovery of cotransport led directly to the development of oral rehydration therapy. This treatment counterbalances the loss of water and electrolytes caused by cholera via a glucose containing salt solution that accelerates water and electrolyte absorption. This is possible because cholera does not interfere with sodium-glucose cotransport.
Oral rehydration therapy saves the lives of millions of cholera patients in underdeveloped countries since the 1980s. In 1978, The Lancet wrote: "the discovery that sodium transport and glucose transport are coupled in the small intestine, so that glucose accelerates absorption of solute and water, was potentially the most important medical advance this century."
Not to be confused with Bob Crane of Hogan's Heroes.
"United States Census, 1940," database with images, FamilySearch (https://familysearch.org/ark:/61903/1:1:K7FD-G8J : 14 March 2018), Robert K Crane in household of Mary E Crane, Chestertown, Election District 4, Kent, Maryland, United States; citing enumeration district (ED) 15-8, sheet 8B, line 72, family 212, Sixteenth Census of the United States, 1940, NARA digital publication T627. Records of the Bureau of the Census, 1790 - 2007, RG 29. Washington, D.C.: National Archives and Records Administration, 2012, roll 1552.
"United States Social Security Death Index," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:JK4C-MTR : 20 May 2014), Robert K Crane, 31 Oct 2010; citing U.S. Social Security Administration, Death Master File, database (Alexandria, Virginia: National Technical Information Service, ongoing).
Find a Grave, database and images (https://www.findagrave.com : accessed 04 May 2020), memorial page for Dr Robert Kellogg Crane (20 Dec 1919–31 Oct 2010), Find A Grave: Memorial #61238982, citing Evergreen Cemetery, Hillside, Union County, New Jersey, USA ; Maintained by Carole McCaig (contributor 46785778) .
https://en.wikipedia.org/wiki/Robert_K._Crane
https://prabook.com/web/robert_kellogg.crane/700481
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Categories: Biochemists | Notables